This drawing represents a variability map of the eukaryotic LSU rRNA molecule superimposed on a secondary structure model of Saccharomyces cerevisiae. The variability of individual nucleotides is calculated by substitution rate calibration (Van de Peer et al. 1996a) and indicated by colored beads. Nucleotides are divided into 5 variability classes ranging from very conserved (blue) to very variable (red) as indicated in the legend. Positions that are identical in all organisms taken into account are indicated in purple. Positions which are deleted in more than 25% of these organisms or for which the alignment was unreliable were not taken into account. These positions are colored grey. This variability map was first published in Ben Ali et al. 1999.

Document last updated: Tue Jul 15 12:00:40 MEST 2003